Statins deplete vitamin E and coenzyme Q10 levels in type two diabetic patients

This study was published in Clinica Chimica Acta 2001 Sep 25;311(2):91-4

 

Study title and authors:

Effect of atorvastatin on LDL oxidation and antioxidants in normocholesterolemic type 2 diabetic patients.

Oranje WA, Sels JP, Rondas-Colbers GJ, Lemmens PJ, Wolffenbuttel BH.

Department of Endocrinology and Metabolism, University Hospital Maastricht, Maastricht, The Netherlands. Oranje@rdgg.nl

 

This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/11566168

This study investigated the effects of statins in type two diabetic patients. The three month study included 19 patients who received either atorvastatin or placebo.

The study found:
(a) The alpha-tocopherol (vitamin E) levels of patients receiving atorvastatin reduced by 38%.
(b) The ubiquinol (ubiquinol is the active form of coenzyme Q10) levels of patients receiving atorvastatin reduced by 37%.