Statins unequivocally associated with lower levels of testosterone

This study was published in Endokrynologia Polska 2014;65(6):464-8

 

Study title and authors:

Treatment with statins and testosterone levels in men.

Mędraś M, Kubicka E, Jóźkow P, Słowińska-Lisowska M, Trzmiel-Bira A, Filus A.

Department of Biological Principles of Sport, University School of Physical Education in Wroclaw, Wroclaw, Poland. eliza.kubicka@gmail.com.

 

This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/25554614

The aim of the study was to evaluate whether the use of statins is associated with the concentration of sex hormones. The study included 237 men, average age 58 years.

the study found:
(a) The total testosterone levels of men taking statins was 9% lower than men not taking statins.
(b) The free testosterone levels of men taking statins was 18% lower than men not taking statins.
(c) The calculated free testosterone levels of men taking statins was 11% lower than men not taking statins.
(d) The bioavailable testosterone levels of men taking statins was 19% lower than men not taking statins.

Medras concluded: "Our study unequivocally confirms that the use of statins is associated with lower levels of: total testosterone, free testosterone, calculated free testosterone and bioavailable testosterone".