Statins associated with elevated risk of high-grade prostate cancer

This study was published in the European Journal of Cancer 2015 Feb 23. pii: S0959-8049(15)00124-0

 

Study title and authors:

The risk of prostate cancer for men on aspirin, statin or antidiabetic medications.

Nordström T, Clements M, Karlsson R, Adolfsson J, Grönberg H.

 

This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/25727881

This study estimated the association between prescribed medications and the risk of either any prostate cancer or high-grade prostate cancer. The study included 185,667 men having a first recorded prostate specific antigen test and 18,574 men having a first prostate biopsy.

Regarding statins, the study found:
(a) Men using statins had a 16% increased risk of any prostate cancer compared to men not taking statins.
(b) Men using statins had a 25% increased risk of high-grade prostate cancer compared to men not taking statins. 

Nordstrom concluded: "Use of any statins was associated with an elevated risk of being diagnosed with high-grade prostate cancer".