Cardiac surgery patients taking statins have a 24% increased risk of death

This study was published in Clinical Infectious Diseases 2009 Apr 1;48(7):e66-72

Study title and authors:
Preoperative statin use and infection after cardiac surgery: a cohort study.

Mohamed R, McAlister FA, Pretorius V, Kapoor AS, Majumdar SR, Ross DB, Norris CM
Department of Medicine, Division of General Internal Medicine, University of Alberta, Edmonton, Alberta, Canada.

This study can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/19228110

This study explored the effects of preoperative statin use in adults who had undergone cardiac surgery. The study included 7,733 nontransplant cardiac surgery patients who were followed for 30 days.

The study found:
(a) Patients taking statins had a 24% increased risk of death compared to patients not taking statins.
(b) Patients taking statins had an 11% increased risk of death due to infection compared to patients not taking statins.
(c) Patients taking statins had an 8% increased risk of any infection compared to patients not taking statins.

 

 

Links to other studies:

Statin treatment increases the risk of death by 301% after balloon angioplasty

Statins should not be given to patients with heart failure

Statin use is associated with an 80% higher risk of multiple organ failure in severely injured blunt trauma patients